2022 ASH – Characterization of ELA026, a Clinical-Stage Monoclonal Antibody That Rapidly and Potently Depletes Myeloid Cells and T Lymphocytes

Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening syndrome of excessive immune activation. The disease is associated with a massive systemic inflammatory response requiring immediate and aggressive treatment. Secondary HLH (sHLH) is triggered…